Comprehensive medicinal chemistry

by Gil, Carmen Martinez, Ana

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Title Statements

Full title :Comprehensive medicinal chemistry. / volume editors: Ana Martinez, Centro de Investigaciones Biologicas-CSIC, Madrid, Spain, Carmen Gil, Centro de Investigaciones Biologicas-CSIC, Madrid, Spain.

Summary

Comprehensive Medicinal Chemistry III, Third Edition provides a contemporary and forward looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry.