Drug-like properties: concepts, structure design and methods : from ADME to toxicity optimization

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This volume provides a practical understanding of property fundamentals, effects, structure-property relationships, and structure modification strategies that can be applied to improving leads. Property assays are discussed because of the crucial nature of method selection and understanding of the data for informed decisions.

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Title Statements

Full title :Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization / by Li Di, Edward H. Kerns.

Summary

Edition Statements

Publication Date:2016
Edition:Second edition

Publication Statements

Publisher(s):Elsevier/AP
Place of Publication:Amsterdam
Language:eng
Publication Date:2016

Notes

Originally published as: Drug-like properties / Edward H Kerns, Li Di. 2008.

The Physical Object

Description:xx, 560 pages : : illustrations ; : 29 cm

Edition Identifiers

ISBN:9780128010761, 0128010762
oclc:ocn955091005
LC Classification:RS420
Dewey Decimal:615.1/9

Subjects

Chemistry, Pharmaceutical Chimie pharmaceutique Drug Design Drug development Drug Evaluation, Preclinical Drug-Related Side Effects and Adverse R… Drugs -- Design Drugs -- Side effects Drugs -- Structure-activity relationshi… Health and Fitness Health and Wellbeing Médicaments -- Conception Médicaments -- Développement Médicaments -- Effets secondaires Médicaments -- Relations structure-acti… Pharmaceutical chemistry Pharmaceutical Preparations -- metaboli… Pharmacocinétique Pharmacokinetics Relations structure-activité (Biochimie)