Mesenchymal stem cell in veterinary sciences

This book focuses on mesenchymal stem cells (MSCs) of animal origin, including their isolation, characterization, and clinical applications. After briefly discussing the historical development of the field of stem cell research, it describes the basic properties and nature of stem cells particularly in relation to MSCs. In turn, it reviews materials and methods used to isolate MSCs from various sources, culture expansion, characterization and long-term storage. It also explores the therapeutic efficacy, immunomodulation and anti-inflammatory, and differentiation properties of MSCs. Importantly, the book discusses the applications of genetic engineering to enhance the efficacy and potential of MSCs in regenerative medicine. The book largely addresses the potential applications of mesenchymal stem cells in therapies for important species of domesticated animals including sheep, goats, cattle, buffalo, cats, dogs and horses. Finally, the book presents an abridgement of challenges and future prospects of stem cell research and application in medicine, in general and veterinary sciences, in particular.

1 Brief Stem Cell Developmental History -- 2 Stem Cell And Its Properties -- 3 Mesenchymal Stem Cell Isolation, Culture, Characterization And Cryopreservation -- 4 Mesenchymal Stem Cell Immuno-Modulation And/ Anti-Inflammatory Properties -- 5 Mesenchymal Stem Cell Properties And Available Micro-Environment -- 6 Mesenchymal Stem Cell Genetic Engineering And Regenerative Medicine -- 7 Sheep Mesenchymal Stem Cell Basic Research And Potential Applications -- 8 Goat Mesenchymal Stem Cell Basic Research And Potential Applications -- 9 Cattle/Buffalo Mesenchymal Stem Cell Basic Research And Potential Applications -- 10 Cat Mesenchymal Stem Cell Characteristics And Potential Applications -- 11 Dog Mesenchymal Stem Cell Basic Research And Potential Applications -- 12 Equine Mesenchymal Stem Cell Basic Research And Potential Applications -- 13 The Future Of Mesenchymal Stem Cell Research.