Platelets

Platelets is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. Comprehensive and definitive source of knowledge about platelets for clinicians, pathologists and scientists Integrates the entire field of platelet biology, pathophysiology, and clinical medicine Full color reference comprising 64 chapters, 1400 pages, and 16,000 references Contributions from 126 world leaders in their fields New chapters on topics such as the regulation of platelet life span, platelet microRNAs, GPVI and CLEC-2, monitoring of antiplatelet therapy, novel antiplatelet therapy, and making platelets ex vivo.

Previous edition: 2007.

I. Platelet biology. The evolution of mammalian platelets / Jack Levin -- Megakaryocyte development and platelet formation / Joseph E. Italiano Jr. and John H. Hartwig -- The regulation of platelet life span / Emma C. Josefsson [and others] -- Platelet genomics / Paul F. Bray [and others] -- Platelet microRNAs / Patrick Provost -- the platelet proteome / Matthew C. Smith [and others] -- Platelet structure / James G. White -- The platelet cytoskeleton / John H. Hartwig -- Platelet receptors / Kenneth J. Clemetson and Jeannine M. Clemetson -- The GPIb-IX-V complex / Robert K. Andrews and Michael C. Berndt -- GPVI and CLEC-2 / Alice Y. Pollitt, Craig E. Hughes, and Steve P. Watson -- Integrin [alpha]IIb[beta]3 / Kamila Bledzka [and others] -- Protease-activated receptors / Ping Zhang, Lidija Covic, and Athan Kuliopulos -- The platelet P2 receptors / Marco Cattaneo -- PECAM-1 / Peter J. Newman and Debra K. Newman -- Interactions between platelets, leukocytes and the endothelium / Virgilio Evangelista and Susan S. Smyth -- Inhibition of platelet function by the endothelium / Lea M. Beaulieu and Jane E. Freedman -- Platelet secretion / Robert Flaumenhaft.

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