Toxicogenomics
by Inoue, T., (Tohru) Pennie, W. D., (William D.)
Toxicogenomics is a new multidisciplinary field concerned with elucidating how the entire genome is involved in biological responses of organisms exposed to environmental toxicants and stressors. Toxicogenomics combines information from studies of genomic-scale mRNA profiling by microarray analysis, cell-wide or tissue-wide protein profiling (proteomics), genetic susceptibility related to single nucleotide polymorphism, and computational models to understand the roles of gene-environment intera…
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- Full title :Toxicogenomics / T. Inoue, W.D. Pennie, eds.
Summary
Toxicogenomics is a new multidisciplinary field concerned with elucidating how the entire genome is involved in biological responses of organisms exposed to environmental toxicants and stressors. Toxicogenomics combines information from studies of genomic-scale mRNA profiling by microarray analysis, cell-wide or tissue-wide protein profiling (proteomics), genetic susceptibility related to single nucleotide polymorphism, and computational models to understand the roles of gene-environment interactions. This book makes a valuable addition to the laboratory bookshelf of all scientists and practitioners studying toxicology, environmental science, drug development, and pharmaceutical safety. As toxicogenomics makes a revolutionary impact on environmental health, drug safety, and risk assessment in 21st-century toxicology, this volume serves as an essential sourcebook.
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- Publication Date:©2003.
Publication Statements
- Publisher(s):Springer
- Place of Publication:Tokyo
- Language:eng
- Publication Date:©2003.
The Physical Object
- Description:1 online resource (xxii, 228 pages) : : illustrations (some color)
Edition Identifiers
- ISBN:9784431669999, 443166999X, 9784431670018, 4431670017
- DOI:10.1007/978-4-431-66999-9
- oclc:ocn607139839
- LC Classification:RA1224.3
- Dewey Decimal:616/.042
Table of Contents
Introductory Keynotes -- Strategy for Toxicogenomics -- Technical Development (Genomics and Proteomics) -- Experimental Applications (1) -- Oncology Research -- Experimental Applications (2) -- Xenobiotic Metabolism -- Experimental Applications (3) -- Endocrine Disruptor Research -- Future Prospects and Risk Assessment -- Index.
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