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This book summarizes current research on the role of signal transduction pathways in cancer and its implications for the development of more effective anticancer agents. Material is divided into four sections reflecting physiological groupings, focusing on receptors at the cell …
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their n…
3-Methylindole (3MI) is a selective pneumotoxicant that induces lung injury in all test animals. 3MI's pneumotoxicity is largely dependent on P450 bioactivation to produce 3-methyleneindolenine (3MEI). 3MEI is an unstable reactive intermediate that can readily alkylate macromole…
Iron is an essential nutrient of cells and is utilized in metabolic processes and in cell proliferation. However, iron overload has been associated with increased risk for cancer, including breast cancer. Redox cycling of catecholestrogen metabolites between quinone and hydroqui…
Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alt…
During the past decade, a significant amount of research has been conducted on phytopharmaceuticals. Today, a growing body of evidence demonstrates the efficacy of a wide variety of natural products and affirms their potential in the treatment of cancer. Phytopharmaceuticals in …
Phytopharmaceuticals in cancer chemoprevention
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Type: Book
During the past decade, a significant amount of research has been conducted on phytopharmaceuticals. Today, a growing body of evidence demonstrates the efficacy of a wide variety of natural products and affirms their potential in the treatment of cancer. Phytopharmaceuticals in …