"This detailed volume focuses on the CRISPR-associated guide RNA and how it can be designed, modified, and validated for a broad repertoire of purposes. Beginning with a section on computational design of target-specific guide RNAs, the book continues by covering chemical modifi…
"Bringing together historical and ethical insights on the revolutionary, Nobel prize winning CRISPR/Cas9 gene editing technology, this accessible book examines the history of human attempts to understand and control our evolution, how the CRISPR/Cas9 technology works and what it…
"Bringing together historical and ethical insights on the revolutionary, Nobel prize winning CRISPR/Cas9 gene editing technology, this accessible book examines the history of human attempts to understand and control our evolution, how the CRISPR/Cas9 technology works and what it…
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusi…
This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic informat…
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusi…