The astonishing account of the decades-long cocaine use of Sigmund Freud and William Halsted. The author discusses the physical and emotional damage caused by the constant use of the then-heralded wonder drug, and of how each man ultimately changed the world in spite of it--or b…
Addiction is characterized by abnormal, long-term molecular alterations in specific brain regions in response to drugs of abuse which lead to life-long behavioral abnormalities(1). Epigenetic mechanisms play a key role in the dynamics of molecular alterations that control gene e…
Decision making is an important cognitive process that can become dysfunctional when exposed to drugs of abuse. Those who suffer from substance use disorders often have increased rates of impulsivity, including delay discounting, a type of impulsivity comprised of magnitude and …
Previous work indicates that the infralimbic cortex (IL) mediates extinction learning and actively suppresses cocaine-seeking during reinstatement, following cocaine self-administration. Despite extensive work supporting this role for IL activity, how and under exactly which con…
"Blow, snow, crack ... Whatever you call it, cocaine is a big problem in the United States and Canada. More than a million individuals in the United States can be classified as being addicted to cocaine. "Cocaine: The Rush to Destruction" tells the story of cocaine, its history …
A comprehensive review of the chemical, clinical, pharmaco-logical, medical and social aspects of the chemicals that are widely abused is presented in this highly informative publication. The contributing authors represent expertise in clinical medicine, pharmacy, chemistry, pha…
Atualmente, a Realidade Virtual (RV) apresenta-se como uma tecnologia com um enorme potencial e cada vez se verifica mais a sua presença em várias áreas. Uma vez que a Arquitetura é uma dessas áreas, a presente dissertação pretende aplicar e explorar a tecnologia digital de RV, …
