Human immunosenescence contributes to morbidity and mortality in later life. This title collects papers that address the mechanisms responsible for immune ageing in humans and considers what might be accomplished to redress the erosion of immune competence with age.
Genome architecture and sequence variation in health and disease -- Genes and transcripts : insight into regulation at different levels -- Modifications : epigenetics and epigenomics -- Gene environment interactions : damage and control -- Phenotypes, phenocopies, pathways, and …
Examines the progress made in genetics and genomics, covering diseases, medicine and therapies, and more.
by Donaldson, Peter, Daly, Ann K., Ermini, Luca, Bevitt, Debra
Genetic diversity -- Defining complex disease -- How to investigate complex disease genetics -- Why investigate complex disease genetics -- Statistical analysis in complex disease : study planning and data handling -- The major histocompatibility complex -- Genetics of infectiou…
by Donaldson, Peter, Ermini, Luca, Bevitt, Debra, Daly, Ann
by Donaldson, Peter, Daly, Ann K., Ermini, Luca, Bevitt, Debra
Genetics of Complex Disease examines how the identification of genetic variations that increase or reduce the risk of common, genetically complex, diseases can be used to improve our understanding of the pathology of many common diseases; enable better patient management and car…
Fibrinolysis in Disease reviews the state of the art of basic and clinical aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books.The Malignant Process, Interventions in Thrombogenic Mechani…
The issue of male germ line mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile over recent years. Mutations are thought to be becoming more prevalent as a result of: exposure to chemicals in the environment, anti canc…
"This volume presents detailed laboratory procedures in an easy to follow format that can be carried out with success by investigators lacking previous exposure to a specific research method. Chapter guide readers through the application of molecular approaches to disease gene i…
