What's the difference between being possessed by Satan and hallucinating that you're possessed by Satan? To an 11-year old boy who's heard all about The Exorcist, nothing at all. Go to Hell and back with Steve Kissing in this autobiographical graphic novel that proves that real …
Fifty million people worldwide have epilepsy and yet up to 35% of patients experience seizures that are resistant to anti-epileptic drugs. Patients with medication-resistant epilepsy have increased risks of premature death, psychosocial dysfunction and a reduced quality of life.…
Introduction Although the relationship between mental disorders and epilepsy has been studied for several years there is a lack of systematization of knowledge in this area. People with epilepsy, particularly those who are refractory to pharmacological treatment, have a high pre…
Background: It has long been accepted that the environment we experience can impact our well-being; throughout recorded history, the greatest prevalence and severity of disease has been experienced by marginalized and underserved populations. However, the translation of such non…
Background: Epilepsy monitoring units (EMUs) provide a safe environment for forming a more illustrative understanding of the patient’s seizure disorder. Patients are admitted to EMUs usually for several days at a time. Upon admission, electroencephalogram (EEG) electrodes are pl…
Epileptic disorders manifest with seizures and interictal epileptiform discharges (IEDs). The hemodynamic and metabolic changes that accompany IEDs may be critical for epileptogenesis but they are poorly understood. This thesis aims to characterize such changes. Given the unpred…
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a prevalence of approximately 1% children worldwide. ASD is characterized by deficits in social communication and interaction and the presence of restricted interests and repetitive behaviours. Genetic alterati…
Emerging implantable microdevices hold great promise for the treatment of patients with neurological conditions. These biomedical systems have been exploited as unconventional treatment for the conventionally untreatable patients. Recent progress in brain-machine-interface activ…
Applying data mining techniques on medical databases which contain un-structured and semi-structured data is a challenging task. It is not only due to the complexity of such databases but also due to the characteristics of the medical domain. This thesis describes how multiple l…
Epilepsy, one of the most common neurological disorders, affects roughly 1% of the world's population. Despite ongoing research and the development of new pharmacological treatments, a significant number of patients' seizures remain inadequately controlled. This short-coming ref…
Developmental cortical malformations are a major cause of intractable seizures. Determining the location and timing of susceptibility for epileptiform activity is critical to identifying what mechanisms contribute to epileptogenesis in any model. Using the freeze lesion rat mode…
Amaç: Bu çalışmanın amacı epilepsi cerrahisi geçirmemiş fokal kortikal displazili nöbet hastalarında lezyon yeri, kullanılan tedavi seçeneklerinin belirlenmesi, en çok tercih edilen farmakoterapi ajanının ve tedavi başarısının belirlenmesidir. Gereç ve Yöntem: Marmara Üniversite…
Intractable epilepsy that remains resistant to drug treatment is a significant public health problem with very few alternative therapeutic options besides surgery. The goal of this research is to investigate hypothesized mechanisms of epileptogenesis and to explore innovative tr…
Epilepsy is one of the most frequent neurological afflictions world-wide. Due to the vast complications with current treatment, there is a high demand for more effective and safer antiepileptic drugs. In this study, three novel series of para -substituted N-benzenesulfonamide en…
Epilepsy in Medieval Islamic History focuses on the perception, etiology and treatment of epilepsy in the work of four medieval Islamic scholars, Ibn Sina, Razi, Ibn Qayyim and S[dotbelow]anawbari, while attempting to place their views in the wider context of a medieval Islamic …
Unique to the market and expanded and revised, this definitive text describes the many causes of epilepsy. It is the only single source of information, designed for clinical practice and written by leading figures from the field. This new edition has been fully revised and expan…
Functional neurosurgery focuses on improving the lives of patients with epilepsy, movement disorders, pain, and psychiatric illnesses. In recent years, approaches ranging from open surgery to minimally invasive techniques have been leveraged to improve daily functioning and qual…
