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An overview of quantitative genetics; Properties of distributions; Covariance, regression, and correlation; Properties of single loci; Sources of genetic variation for multilocus traits; Components of environmental variation; Resemblance between relatives; Introduction of matrix…
This first of a two-volume set on the theoretical and empirical applications of quantitative genetics focuses on the basic biology and methods of analysis of quantitative characters. The authors endeavor to develop central theoretical concepts from first principles. They also ou…
Historical overview. Principles of parameter estimation. Random and fixed effects, the mixed model. Experimental designs to detect QTL, generation of linkage disequilibrium. QTL parameter estimation for crosses between inbred lines. Advanced statistical methods for QTL detection…
Introduction. Biology in genomics. Introduction to genomics. Statistics in genomics. Single-locus models.Two-locus models: the controlled crosses. Two-locus models: netural populations. Two-locus models: using linkage disequilibrium. Linkage grouping and locus ordering. Multi-lo…