Annotation This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practi…
Iron is essential for most forms of life, including humans. On the other hand, iron is also potentially toxic. Therefore, the control of iron metabolism and maintenance of iron hemostasis is an crucial part of many aspects of human health and disease. Iron deficiency anemia is o…
Presents various treatment options for patients with myeloma. This book reviews basic mechanism of the disease and shows how these mechanisms can best be targeted.
Myelodysplastic syndromes (MDS) are a group of clonal disorders characterized by pancytopenias and the risk of progression to acute myeloid leukemia. The diagnosis of MDS can be challenging, while the outcomes of MDS patients vary widely. This book provides a concise yet compreh…
Adolescent females experience a variety of blood disorders that are often unique to this patient population. As they go through puberty, they are uniquely poised to encounter various bleeding and thrombotic disorders once they attain menarche, start to have menstrual bleeding, a…
This volume provides a comprehensive and state-of-the-art overview of the major issues specific to managing bleeding patients. The sections of the book have been structured to review the overall scope of issue, among them bleeding conditions, managing bleeding including clearing…
This unique book is the first on pediatric hematopoietic stem cell transplantation that is especially intended for pharmacists - in recognition of the fact that Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice, yet pharm…
Immune thrombocytopenia is a blood disorder, characterised by low platelet count, bleeding and bruising. In children, symptoms are generally mild and spontaneous remission is common. Literature relating to other paediatric conditions is reviewed and considered alongside limited …
The unfolded protein response (UPR) is a complex signalling pathway activated in response to endoplasmic reticulum stress. In recent years, the UPR has been implicated in cancer and chemosensitivity, particularly in solid tumours. This thesis investigated the potential value of …
Despite improved treatments for Non-Hodgkin’s Lymphoma (NHL) and Multiple Myeloma (MM), most patients eventually relapse and these diseases remain largely incurable. This has precipitated recent research into more clinically relevant in vitro models to enable development of more…
Since the first successful transplantation of umbilical cord blood in 1988, cord blood has become an important source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Significant progress has been accompanied by challenges for scientis…
Hematopathology: Genomic Mechanisms of Neoplastic Diseases will keep physicians abreast of the rapid and complex changes in genomic medicine, as exemplified by the molecular pathology of hematologic malignancies. This timely volume will update physicians on the complexities of g…
The Textbook of Coronary Thrombosis and Thrombolysis, in essence, represents a heartfelt gift of knowledge from a dedicated group of scientists and clinicians, who collectively have set out on a mission to minimize the societal impact of `hemostasis in the wrong place.' The book…
