In vivo electrophysiology

Previous work indicates that the infralimbic cortex (IL) mediates extinction learning and actively suppresses cocaine-seeking during reinstatement, following cocaine self-administration. Despite extensive work supporting this role for IL activity, how and under exactly which con…

Alzheimer’s disease (AD) is a neurodegenerative disorder, characterised by severe memory loss and the accumulation of amyloid-beta (Aβ) and tau pathology within neocortex and medial temporal lobe (MTL) structures. Episodic memory impairment is a defining feature of early AD. The…