A comprehensive book on insulin and cancer.
This volume, written by renowned experts, provides complete coverage of the main genetic conditions associated with diabetes. Divided into five sections, it offers insights into genetic defects involving the pancreatic beta cell, extreme insulin resistance, ciliopathies, obesity…
Gestational diabetes mellitus and hypertensive disorders in pregnancy are serious maternal health conditions with immediate and lifelong mother-child health consequences. These obstetric pathologies have been widely investigated, but mostly in silos, while studies focusing on th…
Metabolic syndrome (MetS) is a cluster of symptoms that increase risk for heart disease and type 2 diabetes. Therefore, early detection of MetS is vital for disease prevention. Gestational diabetes (GDM) and/or obesity during pregnancy are associated with a greater risk for MetS…
Type 2 diabetes (hereafter, diabetes) and prediabetes are very common in older adults and constitute a great health concern for this population. The objective of this project is to investigate the impact of prediabetes and diabetes on health and survival among older adults, and …
Life history theory dictates that organisms should precisely allocate investment of their limited resources, including energy, to a variety of tasks to serve natural selection’s ultimate goal: reproduction. In adolescence, menarche occurs as growth velocity is tapering off, prov…
Diabetes mellitus, commonly referred to as “diabetes,” is characterized as elevated blood glucose levels resulting from the body’s inability to produce insulin or cells’ compromised sensitivity to insulin. Type 2 diabetes is a compromised sensitivity to insulin or insulin resist…
The overall aim of the work presented in this thesis was to further characterise aspects of metabolic and immune system cross-talk in human subcutaneous adipose tissue, with a particular emphasis on the potential role of T-lymphocytes in adipose tissue dysfunction and insulin re…
Background and objective: Childhood obesity is a serious global health problem and it is associated with insulin resistance and significantly increased risk for development of type 2 diabetes and cardiovascular disease. Metformin reduces the risk of developing T2D in adult patie…
In this highly readable and provocative book, Dr. Jason Fung sets out an original, robust theory of obesity that provides startling insights into proper nutrition. Flying in the face of the weight-loss recommendations that have failed in the past, this book reveals that obesity …