Mesenchymal stem cell in veterinary sciences
This book focuses on mesenchymal stem cells (MSCs) of animal origin, including their isolation, characterization, and clinical applications. After briefly discussing the historical development of the field of stem cell research, it describes the basic properties and nature of st…
Morphology, cytoskeleton organisation and nuclear states are important biomarkers to characterise and modulate cell behaviours. Bilateral interactions between cells and their surroundings are critical aspects of biology, evidenced by the role of extracellular environment mechani…
Regenerative medicine is an emerging technology and with hundreds of cell therapies currently in clinical trials there is a need to expand the limited knowledge related to their storage, shipment and preservation. The most widely used medium for human cell cryopreservation is 10…
The differentiation of mesenchymal stem cells (MSCs) to endothelium is a critical but poorly understood feature of tissue vascularisation and considerable scepticism still remains surrounding this important differentiation event. Defining features of endothelial cells (ECs) are …
In the first chapter, we focus on the identification and characterization of renal stem cells in the adult kidney. For this purpose, we stained adult kidney cells suspension for a number of markers and using FACS analysis, observed that there are a high level of SCA-1+ Lin− cell…
The objective of this doctoral thesis was to investigate the effects of laminar fluid shear stress on the function three types of adult stem cells: mesenchymal stem cells, neural crest stem cells and multipotent vascular stem cells. These three types of stem cells represent pote…
Recent research has demonstrated a strong correlation between the differentiation profile of mesenchymal stem cells (MSCs) and scaffold stiffness. Chitosan is being widely studied for tissue engineering applications due to its biocompatibility and biodegradability. However, its …