How does a researcher run behavioral assays to find out what's wrong with a mouse? This book answers that question and many more, including what tests are available to discover aberrant behavioral phenotype. Chapters are organized by behavioral domain, including measurements of …
This new edition of Whats Wrong With My Mouse? continues to provide the most thorough overview of mutant mouse technology and a readable introduction to the field of behavioural neuroscience as applied to behavioural phenotyping of transgenic and knockout mice.
[Publisher-supplied data] Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such m…
Technological advances in manipulating the mouse genome has led to the development of sophisticated genetically-engineered models of human cancer that recapitulate many molecular, biologic and histologic features of human tumors. This book provides an overview of the design cons…
Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects…
Technological advances in manipulating the mouse genome has led to the development of sophisticated genetically-engineered models of human cancer that recapitulate many molecular, biologic and histologic features of human tumors. This book provides an overview of the design cons…
Humanized mice
by Nomura, Tatsuji, Watanabe, Takeshi, Habu, Sonoko
fromCurrent Topics in Microbiology and Immunology
Humanized mice
by Nomura, Tatsuji, Watanabe, Takeshi, Habu, Sonoko
fromCurrent Topics in Microbiology and Immunology
The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be …
Humanized mice
by Nomura, Tatsuji, Watanabe, Takeshi, Habu, Sonoko
fromCurrent Topics in Microbiology and Immunology
Humanized mice
by Nomura, Tatsuji, Watanabe, Takeshi, Habu, Sonoko
fromCurrent Topics in Microbiology and Immunology
In a humanized mouse transplanted human tissues and cells show the same biological function as they do in the human body. It has become possible to study the pathophysiology and treatment of human diseases in mice with excellent reproducibility, a remarkable breakthrough. Unsurp…
Annotation In a humanized mouse transplanted human tissues and cells show the same biological function as they do in the human body. It has become possible to study the pathophysiology and treatment of human diseases in mice with excellent reproducibility, a remarkable breakthro…