Thesiss

The effects of aflatoxin B1 (AFB1 ) in turkeys is well documented; however, the specifics of AFB1 metabolism in this species have not been investigated. The extreme sensitivity of turkeys to the hepatotoxic effects of AFB1 makes them an ideal candidate for chemoprevention studie…

The mycotoxin Aflatoxin B1 (AFB1 ) has been shown to result in potent hepatotoxic and carcinogenic effects in many animal species. AFB1 undergoes metabolic conversion by cytochrome P450 (CYP) to a highly reactive AFB1 -8,9-epoxide (AFBO). Turkeys are extremely sensitive to AFB1 …