Childhood stunting remains a significant public health challenge with adverse developmental and health outcomes in life and over generations. Efficacious dietary interventions have not achieved full linear growth in height deficient children. This dissertation explores novel cau…
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The mycotoxin Aflatoxin B1 (AFB1 ) has been shown to result in potent hepatotoxic and carcinogenic effects in many animal species. AFB1 undergoes metabolic conversion by cytochrome P450 (CYP) to a highly reactive AFB1 -8,9-epoxide (AFBO). Turkeys are extremely sensitive to AFB1 …
The major histocompatibility complex (MHC) is a genomic region encoding for genes with various immune functions in vertebrates. Although this region has been studied extensively in humans, mice and agriculturally important species such as cattle, horses and chickens, the organiz…
Aflatoxin, produced by the fungi Aspergillus flavus and A. parasiticus, is the most potent naturally occurring human hepatocarcinogen. Food crops colonized by these fungi, especially maize and groundnut, are the major sources of dietary aflatoxin exposure. Aflatoxin and chronic …