Prognostic factors come in a variety of forms and may be patient, tumour or environmental related. This thesis examines the interaction of prognostic factors for a variety of tumour types. It particularly focuses on single nucleotide polymorphisms (SNPs) of the vascular endothel…
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In this thesis, the use of verotoxin1 as a new approach to the management of certain human neoplasms and its mechanism of action in causing cell death is discussed. VT1 cytotoxicity was demonstrated on human cervical cancer, astrocytoma and ovarian tumor and multidrug resistant …