The synthesis and characterization of water-soluble zwitterionic poly(tyrosine), dendronized analogues of the same polymer, and non-ionic triethylene glycol (TrEG) -based dendritic macromoledules are investigated. Poly(tyrosine) linked through the phenol groups is synthesized un…
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Amphiphilic hydrogels with different molecular architecture were successfully synthesized by two methods: (1) Williamson ether synthesis with linear or hyperbranched poly [(p-chloromethyl) styrene], PPCMSt and poly(ethylene glycol), PEG, and (2) nucleophilic substitution reactio…
This dissertation consists of three main parts, totaling five chapters, and focuses on developing novel nucleosides via "click" chemistry and studying their potential biological properties. Chapter three describes the synthesis and properties of coumarin-modified fluorescent DNA…