Thesiss

We investigated mechanism of resistance to both faslodex and tamoxifen in a panel of 14 ER+ breast cancers cell lines. Growth inhibition assays indicated that some cell lines in the panel are significantly more sensitive to faslodex than to tamoxifen while other cell lines are e…

Prostate cancer (PCa) is the fifth leading cause of cancer-related deaths amongst men worldwide. Androgen deprivation therapy (ADT) in combination with radiation therapy (XRT) is the standard of care for high-risk localized PCa. Unfortunately, most patients become resistant to A…