Thesiss

Astrocytes maintain ion and neurotransmitter homeostasis within the central nervous system. They do so by expressing channels, receptors and transporters such as excitatory amino acid transporters (EAATs) along their highly ramified arbours. EAATs are well known to be glutamate …

Interindividual differences in neurobehavioral response to sleep loss are ubiquitous and unexplained. Numerous factors have been examined as potential predictors of phenotypic response to sleep loss but none have yielded a comprehensive view of the phenomenon. This dissertation …