Thesiss

The purpose of this work was to investigate the interaction of the pro-inflammatory cytokine, IFN-γ, and the anti-inflammatory cytokines, TGF-β and IL-10, in the subclinical and clinical stages of Johne's disease. A retrospective quantitative analysis of IFN-γ, IL-10 and TGF-β m…

The interaction between epithelial cells and macrophages is integral to mucosal immune fate: determining the decision between tolerance and immune activation/inflammation. Endotoxin tolerisation (ET) is a circumstance where cells go through a hypo-responsive state, unable to res…