Thesiss

In this thesis, the performance of a miniaturised field asymmetric waveform ion mobility spectrometry (FAIMS) device hyphenated with time-of-flight mass spectrometry is studied and evaluated for analysis of a variety of compounds in different sample matrices. FAIMS is a selectiv…

Mass spectrometry is becoming increasingly popular as a tool for biochemists to probe not only the primary structure of biological molecules, but also their three-dimensional shape. The question remains, however, as to whether these molecules retain significant aspects of their …

Proteomic studies aim to identify, quantify and characterise the full complement of proteins in a cell or organism under a defined set of conditions, and are important to our understanding of cellular mechanisms. However, such studies represent a major analytical challenge. A ty…