The effects of activation of protein kinase C (PKC) on intermediate filaments (IFs) of different cell types were investigated. In primary cultures of murine or rabbit spinal cord, or human fibroblasts, brief exposure to activators of PKC led to the following changes in IFs: (1) …
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Mass spectrometry is becoming increasingly popular as a tool for biochemists to probe not only the primary structure of biological molecules, but also their three-dimensional shape. The question remains, however, as to whether these molecules retain significant aspects of their …
The predictive algorithm Surfaceplot was used to examine glycoprotein D of herpes simplex virus, type 1 (HSV-1) for amino acid residues with a high probability of being exposed on the molecular surface. The most accurate predicted molecular model of calmodulin would be based on …