Thesiss

Inflammation plays a crucial role in protecting the host from infection and tissue injury. However, uncontrolled inflammation contributes to the pathogenesis of major auto-inflammatory diseases. Interleukin-1 (IL-1), a pleiotropic pro-inflammatory cytokine, is a pivotal mediator…

The macrophage is a common target cell for lentiviral infections, including HIV/ SIV. The kupffer cells of the liver are the largest population of resident macrophages in the body and efficiently filter microbial and other harmful products originate from the gut. An emerging fea…