Thesiss

In this thesis, we report on studies that investigated the roles of serotonin (5-hydroxytryptamine; 5-HT) and γ-aminobutyric acid (GABA) in the pathophysiology of mania and in the mechanism of action of the mood stabilizer, divalproex sodium (DVP) using neuroendocrine challenge …

Background: Corticosteroids have been associated with a wide range of psychiatric disturbances, such as mania, agitation, aggression, depression, bipolar and psychosis. Our first aim was to try to quantify the prevalence of each of the most commonly reported psychiatric symptoms…