Thesiss

Optokinetic nystagmus (OKN) is a fundamental gaze-stabilising response in which eye movements attempt to compensate for the retinal slip caused by self-motion. The OKN response consists of a slow following movement made in the direction of stimulus motion interrupted by fast eye…

Longitudinal studies are a useful tool for investigating the course of chronic diseases. Many chronic diseases are progressive and can be characterized by a set of health states. We can improve our understanding of the natural history of the disease by modeling the sequence of v…

Chronic hepatitis C (CHC) is a leading cause of hepatic fibrosis and cirrhosis. Fortunately, treatment has been revolutionized by the recently introduced direct-acting antivirals (DAAs). However, prompt access to DAA therapy remains a challenge owing to exorbitant drug costs, as…