An almost nonparametric approach for the estimation of the mixing proportion in a mixture of two distributions, when we have a vector of observations on each subject, is to define a mixture of binomials. A mixture of binomials can be obtained if the vector or observations is map…
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Identifying latent subgroups in diseases with heterogeneous presentations can be difficult. It is clinically hypothesized that there are multiple types of patients prone to severe exacerbation in Chronic Obstructive Pulmonary Disease. Few studies have considered the longitudinal…