Thesiss

DNA replication is a highly regulated process and governed by the cell cycle machinery, such that chromosomes are replicated once and only once per cell cycle. The question of what determines whether a DNA sequence serves as specific site for replication initiation is largely un…

There are many ways to culture a single celled organism, each way uniquely capable of answering a different biological question. Continuous culture, a form of growing organisms in which fresh medium is continually added to dilute out the doubling microbe, has existed for decades…