Paediatric oncology

This comprehensive and established textbook presents an up-to-date overview of all aspects of managing children with cancer and in its third edition has been completely revised and updated to reflect recent developments in the field. Individual malignancies are given comprehensive coverage, including details of clinical presentation, diagnostic investigations, novel imaging techniques and current management with chemotherapy, radiotherapy and surgery. Current controversies relating to diagnosis and management - a popular feature of previous editions - are presented in boxes for increased emphasis. Content changes to the new edition include a restructured pathology section and new chapters under separate headings of 'advances in therapy' and 'late effects and supportive care'. Retaining a European flavour, but incorporating information from American and other national studies to give an objective and comprehensive overview, the third edition of Paediatric Oncology remains invaluable reading for trainee and practising paediatric oncologists, and nurse specialists, world-wide. [contributors mainly UK and European, plus 1 from US and 1 from Australia].

Cover -- Book title -- Contents -- Contributors -- Preface -- List of abbreviations -- Reference annotation -- PART 1: SCIENTIFIC AND DIAGNOSTIC PRINCIPLES -- 1 Aetiology and epidemiology -- 2 The molecular basis of children's cancers -- 3 Solid tumour pathology and molecular diagnostics -- 4 Pathology of leukaemia -- 5 Pathology of lymphoma -- 6 Radiation biology -- 7 Clinical applications of paediatric radiotherapy -- 8 Cancer chemotherapy and mechanisms of resistance -- 9 Serum markers in tumour diagnosis and treatment -- 10 Design and role of clinical trials -- PART 2: DIAGNOSIS AND MANAGEMENT OF INDIVIDUAL CANCERS -- 11 Acute myeloid leukaemia -- 12 Acute lymphoblastic leukaemia -- 13 Non-Hodgkin's lymphoma -- 14 Hodgkin's disease -- 15 Tumours of the central nervous system -- 16 Retinoblastoma -- 17 Soft tissue sarcomas -- 18 Bone tumours -- 19 Neuroblastoma -- 20 Wilms' tumour -- 21 Germ cell tumours -- 22 Liver tumours -- 23 Langerhans cell histiocytosis -- 24 Rare tumours -- PART 3A: ADVANCES IN THERAPY: MEGATHERAPY -- 25 Allogeneic stem cell transplantation -- 26 Megatherapy with stem cell rescue in solid tumours -- PART 3B: ADVANCES IN THERAPY: TARGETED THERAPY -- 27 No…