Rab GTPases: methods and protocols

by Li, Guangpu, (Molecular biologist)

Type Book

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Title Statements

Full title :Rab GTPases : methods and protocols / edited by Guangpu Li.

Summary

This volume covers the latest technological advances in the characterization of the biosynthesis and functions of Rab GTPases and their regulation by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). The book consists of 28 chapters, and starts with an overview of the Rab GTPase family. The next few chapters describe systematic approaches to the identification and classification of Rabs and Rab GAPs, as well as the detection of Rab isoprenylation and membrane distribution. The last few chapters examine the biochemical and functional properties of individual Rabs in the order of exocytic, recycling, and endocytic Rabs. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Instructive and practical, Rab GTPases: Methods and Protocols approaches each topic with great detail and is a valuable resource for researchers and students interested in the field of Rab GTPases.

Edition Statements

Publication Date:2015

Publication Statements

Publisher(s):Humana Press
Place of Publication:New York
Language:eng
Publication Date:2015

The Physical Object

Description:xiv, 358 pages : : illustrations (some color) ; : 27 cm

Edition Identifiers

ISBN:9781493925681, 1493925687
oclc:ocn900795936
LC Classification:QP609.G83
Dewey Decimal:572/.793

Subjects

Carrier Proteins Facteurs d'échange des nucléotides guan… G proteins G proteins -- Laboratory manuals GTPase-activating protein GTPase-Activating Proteins GTPases -- Manuels de laboratoire Guanine Nucleotide Exchange Factors Guanosine triphosphatase Guanosine triphosphatase -- Laboratory … Laboratory Manual Laboratory manuals Manuels de laboratoire Protéines activant la GTPase Protéines de liaison Protéines G -- Manuels de laboratoire rab GTP-Binding Proteins