"This book is about Mechanistic Enzymology: Bridging Structure andFunction"--
"This book is about Mechanistic Enzymology: Bridging Structure and Function"--
"This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor inte…
Despite considerable variability within the scientific community, allosteric regulation can best be defined functionally as how a macromolecule binds one ligand differently when a second ligand is or is not pre-bound to the macromolecule, which constitutes a vital aspect of prot…
Bioactive conformation
by Peters, T., (Thomas), Evans, S. V., (Stephen V.)
fromTopics in current chemistry
Bioactive conformation
by Peters, T., (Thomas), Evans, S. V., (Stephen V.)
fromTopics in current chemistry
"Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs natura…
"Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of c…
"Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of c…
"Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of c…
This is the first book that attempts to study the origin of cooperatvity in binding systems from the molecular point of view. The molecular approach provides a deeper insight into the mechanism of cooperativity and regulation, than the traditional phenomenological approach. This…
Objective of this study was to evaluate effect of UV-C radiation (0, 1.16 and 3.21 kJ/cm2), pomegranate (Punica granatum) seed essential oil (PGEO) and lemon (Citrus lemonum) plant essential oil (CLEO) on decontamination of Candida albicans, Listeria monocytogenes, Staphylococcu…
Splicing factors bind, in most cases, to a degenerate motif in the pre-mRNA of the target gene and either recruit or repel the spliceosome to/from nearby splice sites. Many splicing factors possess RNA-independent functions, such as protein-protein interactions in cellular compl…