"This book is about Mechanistic Enzymology: Bridging Structure andFunction"--
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"This book is about Mechanistic Enzymology: Bridging Structure and Function"--
"This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor inte…
Objective of this study was to evaluate effect of UV-C radiation (0, 1.16 and 3.21 kJ/cm2), pomegranate (Punica granatum) seed essential oil (PGEO) and lemon (Citrus lemonum) plant essential oil (CLEO) on decontamination of Candida albicans, Listeria monocytogenes, Staphylococcu…
Splicing factors bind, in most cases, to a degenerate motif in the pre-mRNA of the target gene and either recruit or repel the spliceosome to/from nearby splice sites. Many splicing factors possess RNA-independent functions, such as protein-protein interactions in cellular compl…
Computational proteogenomic integrates proteomics with genomics and transcriptomics data and has emerged over the past decade as a useful discipline for functional annotation of genomes. It has been driven by high-throughput technologies from mass spectrometry and next generatio…
It goes without saying that the necessity and utility of knots in our everyday lives is crucial. Humanity used them to symbolise religious beliefs (endless knot in Buddhism) and countless forms of art throughout history (Roman mosaics, Celtic art etc). However, we know them bett…
Group II introns are a class of large, versatile ribozymes that interrupt genetic loci in bacteria, archaea and the organelles of certain eukaryotes. Following transcription, these ribozymes autocatalytically excise themselves through self-splicing. The Ll.LtrB group II intron w…
The Australian sheep blowfly, Lucilia cuprina, and the New World screwworm (NWS), Cochliomyia hominivorax, are devastating insect pests that cause billions of dollars in damage each year. These insects cause myiasis in warm blooded mammals, in which the larvae feed from flesh of…
Bioactive conformation
by Peters, T., (Thomas), Evans, S. V., (Stephen V.)
fromTopics in current chemistry
0
Type: Book
Bioactive conformation
by Peters, T., (Thomas), Evans, S. V., (Stephen V.)
fromTopics in current chemistry
0
Type: Book
Despite considerable variability within the scientific community, allosteric regulation can best be defined functionally as how a macromolecule binds one ligand differently when a second ligand is or is not pre-bound to the macromolecule, which constitutes a vital aspect of prot…
"Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs natura…
