This is the first book that attempts to study the origin of cooperatvity in binding systems from the molecular point of view. The molecular approach provides a deeper insight into the mechanism of cooperativity and regulation, than the traditional phenomenological approach. This…
"This book is about Mechanistic Enzymology: Bridging Structure andFunction"--
"This book is about Mechanistic Enzymology: Bridging Structure and Function"--
"This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor inte…
by Peters, T., (Thomas), Evans, S. V., (Stephen V.)
fromTopics in current chemistry
by Peters, T., (Thomas), Evans, S. V., (Stephen V.)
fromTopics in current chemistry
Despite considerable variability within the scientific community, allosteric regulation can best be defined functionally as how a macromolecule binds one ligand differently when a second ligand is or is not pre-bound to the macromolecule, which constitutes a vital aspect of prot…
"Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs natura…
"Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of c…
"Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of c…
"Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of c…
Computational proteogenomic integrates proteomics with genomics and transcriptomics data and has emerged over the past decade as a useful discipline for functional annotation of genomes. It has been driven by high-throughput technologies from mass spectrometry and next generatio…
The Australian sheep blowfly, Lucilia cuprina, and the New World screwworm (NWS), Cochliomyia hominivorax, are devastating insect pests that cause billions of dollars in damage each year. These insects cause myiasis in warm blooded mammals, in which the larvae feed from flesh of…
