A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery.
This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and developmen…
This volume explores the latest techniques and methods used for performing up-to-date glycosylation research. The chapters in this book are organized into four parts. Part One looks at the latest analytical and bioinformatics technologies that enable the characterization of glyc…
This volume explores the latest techniques and methods used for performing up-to-date glycosylation research. The chapters in this book are organized into four parts. Part One looks at the latest analytical and bioinformatics technologies that enable the characterization of glyc…
This volume presents methods used for the analysis of glycoproteins at different levels-intact, subunit, glycopeptide, and monosaccharide, and discusses and solves most analytical challenges that a scientist working on glycoproteins may come across. The chapters in this book cov…
This volume presents methods used for the analysis of glycoproteins at different levels--intact, subunit, glycopeptide, and monosaccharide--, and discusses and solves most analytical challenges that a scientist working on glycoproteins may come across. The chapters in this book …
"This book presents a definitive overview of fossil and living Metasequoia and was written by sixteen of the world's experts on this important genus. Given the reality of increasing human pressure and the inevitability of global change, efforts to conserve this ancient genus are…
Glycosyltransferases (GTs) are essential for the biosynthesis of complex glycoconjugates and are powerful tools to study the functions of complex glycans in health, development and disease. Complex glycoconjugates, such as glycoproteins, proteoglycans and glycolipids, are assemb…
Handbook of carbohydrate engineering
Thirty-five years after its exposure, HIV is still a global health threat with millions of new infections annually. The goal of our research is to stop the global spread of HIV, first by preventing new HIV infections and then by working to cure existing infections. Chapter one r…
N-linked protein glycosylation involves the transfer of a glycan onto an Asparagine residue (N) of a polypeptide chain. It is common in Eukaryotes and has recently been observed in Prokaryotes, most notably in Campylobacter jejuni. The C. jejuni N-linked glycosylation system is …
Comparability assessments are frequently performed during biopharmaceutical drug development to evaluate the effects of manufacturing process changes on the structural integrity, safety and efficacy of candidate protein drug products. Physiochemical analytical evaluations (an es…
In this revolutionary book, bestselling author and anti-aging expert Dr. Nicholas Perricone reveals a completely new and hidden threat to our looks and our health'and gives us a program to defeat it. Dr. Nicholas Perricone has gotten to the bottom of accelerated aging with the d…