Prostate cancer is the second most common cancer in men worldwide. Of almost 1.3 million newly diagnosed men per year, up to 80% will have localized disease with a characteristically prolonged natural history. Risk stratification and treatment decision-making for these men is cu…
Background: Prostate Cancer (PCa) is the second most common malignancy among men in the world. In Sweden about 10,000 new cases are diagnosed each year. Mortality rates have been rather stable but have declined the past decades due to early diagnosis and treatment at the expense…
Dynamic treatment regimes (DTRs) have gained increasing interest in the field of personalized health care in the last two decades, as they provide a sequence of individualized decision rules for treating patients over time. In a DTR, treatment is adapted in response to the chang…
Salvage therapy for prostate cancer
This book comprehensively covers application of salvage therapy in reuccurrent prostate cancer. Chapters focus on specific issues associated with a range of surgical and oncological management techniques and strategies including hormone therapy, lymphnode dissection, robotic pro…
Salvage therapy for prostate cancer
This book comprehensively covers application of salvage therapy in reuccurrent prostate cancer. Chapters focus on specific issues associated with a range of surgical and oncological management techniques and strategies including hormone therapy, lymphnode dissection, robotic pro…
This study explored the experiences, psychosocial needs and how best to address them after prostate cancer treatment for Black African/Black Caribbean men and their partners in England. Cancer statistics in the United Kingdom show that Black African and Black Caribbean men have …
Replication-selective oncolytic adenoviruses represent a promising anticancer approach with proven efficacy in cancer cell lines and tumour xenografts in vivo. Anti-tumour efficacy, both in preclinical studies and clinical trials, was significantly improved in combination with c…
Prostate cancer (PCa) is a unique and controversial disease. This is at least due to the high prevalence of latent disease, increasing amounts of which is being diagnosed, most of which is indolent and not lead to death, and for which treatment carries significant risks. An incr…
The potential of using FTIR imaging as analytical technique combined with pre-processing and multivariate analysis methods was investigated. FTIR spectroscopy has been used in the past to investigate aspects of prostate cancer cells and tissues, successfully showing the separati…
The feasibility of Fourier transform infrared (FTIR)-imaging spectroscopy as a tool to discriminate samples from patients suffering from benign prostatic hyperplasia (BPH) and prostate cancer (CaP) samples in blood serum was investigated. Prostate cancer is known to be an age re…
In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormonal treatments, assess the actions of new and established agents, and illustrate the new applications of hormonal chemoprevention…
In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormonal treatments, assess the actions of new and established agents, and illustrate the new applications of hormonal chemoprevention…
Background: African Heritage (AH) men have a higher overall incidence, earlier age of onset, more clinically advanced and aggressive disease, higher incidence of metastases and mortality from prostate cancer (CaP) compared to Caucasian men. Biological and genetic factors relatin…
Disease progression manifests through a broad spectrum of statically and longitudinally linked clinical features and outcomes. This leads to heterogeneous progression patterns that may vary greatly across individual patients and makes the survival and quality of a patient’s life…
With around 1.2 million cases per year, prostate cancer is the second most common cancer among men. It is usually a slow growing disease that affects older men. It is also a cancer that is heterogenous, often multifocal, and rarely show symptoms as long as it is localized. All t…
The growth-inhibitory effect of saw palmetto supplements (SPS) with high long-chain fatty acids (FA)-low phytosterols (HLLP), high long-chain FA-high phytosterols (HLHP), and high medium-chain FA-low phytosterols (HMLP) was determined using androgen-sensitive LNCaP prostate canc…
Magnetic nanoparticles (MNPs) were synthesized from Fe2+ and Fe3+ by the co-precipitation method. Two nanoparticle surface coatings (gum arabic and sodium citrate) provided additional functionalization and cell selectivity. The incorporation of surface modifiers to the synthesiz…