"A collection of challenging and unusual cases from the author's extensive experience as a Medical Toxicologist, these cases demonstrate medical problem solving and differential diagnosis in action from the perspective of an experienced clinician. Written in an engaging style an…
"Covers various aspects of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. This book covers individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, bioma…
When a new technology makes people ill, how high does the body count have to be before protective steps are taken? This disturbing book tells a dark story of hazardous manufacturing, poisonous materials, environmental abuses, political machinations, and economics trumping safety…
"The volume presents a variety of protocols that will be useful to researchers working in the field of disease modeling, drug discovery, and the cell biology of various tissues. Chapters in this book cover topics such as requirements and preconditions for using human induced plu…
"This book since first published in 2004 has been a major resource providing insights and practical guidance for the CMC teams to develop an acceptable cost-effective, risk-based CMC regulatory compliance strategy for biopharmaceuticals (recombinant proteins, monoclonal antibodi…
"This second edition book explores breakthrough technologies in the field of drug target identification and validation. The volume emphasizes particularly revolutionary technologies, such as CRISPR-related screening, “big data,” and in silico approaches, as well as in vivo appli…
"This thorough edition explores numerous methodological approaches that can be extremely informative for our understanding of the developmental toxicant mechanisms, characterization of developmental outcomes, and development of potential interventions that are clinically relevan…
"With genetic engineering, systems explored in this book now exist allowing for the simple, efficient, and near universally precise genetic manipulation directly in any organism, including the mouse. Herein, these models are applied to a wide field of disease areas, including di…
