Thesiss

Peroxisomes are ubiquitous organelles found in almost all eukaryotes. They are sensitive to changes in cellular homeostasis and involved in various metabolic processes. Deficiencies in peroxisome function cause severe neurological problems. Here I report, investigation of peroxi…

LIS1 (Lissencephly 1) and its interacting partner Ndel1 (Nuclear Distribution Element Like 1) play pivotal cellular roles, affecting mitosis, cell migration and intracellular transport. They act through modulation of cytoskeletal dynamics and of cytoplsmic Dynein activity. The i…