Thesiss

Peroxisomes are ubiquitous organelles found in almost all eukaryotes. They are sensitive to changes in cellular homeostasis and involved in various metabolic processes. Deficiencies in peroxisome function cause severe neurological problems. Here I report, investigation of peroxi…

The growth of a neuronal dendritic tree depends on the neuron’s internal state and the environment within which it is situated. Different types of neuron develop dendritic trees with specific characteristics, such as the average number of terminal branches and the average length…

In this work the functions of the microtubule motors kinesin-1, -2 and -3 have been analysed in various settings. The reconstitution of microtubule-dependent motor activity in vitro has been primarily used to dissect the contributions of individual motors to cargo motility in tw…