Thesiss

The data presented within this thesis shows the generation and characterisation of a complete-, macrophage/granulocyte- and T cell-specific IFNγR2 deficient mouse mutant. This mutant mouse is a valuable tool in dissecting the mechanism of action of the pleiotrophic cytokine IFNγ…

This thesis comprises a series of studies conducted to elucidate host responses to Marek's disease virus (MDV) in two body compartments; spleen which is a major secondary lymphoid organ involved in elicitation of immune response and feathers, which are the site of virus shedding…