Thesiss

Heart failure is a major health problem of epidemic proportions. The upregulated expression of endothelial cell adhesion molecules in certain regions of the heart after a myocardial infarction (MI) provides a potential avenue for selectively targeting drugs to inflamed tissue. L…

Advances in genetics have empowered gene therapy as a cancer treatment, however there are many challenges to delivering genes specifically to target disease sites. Presented here is the development of a new non-viral gene delivery vehicle, consisting of branched polyethyleneimin…

Proper cell-cell communication through physical contact is crucial for a range of fundamental biological processes including, cell proliferation, migration, differentiation, and apoptosis and for the correct function of organs and other multi-cellular tissues. The spatial and te…