Genome wide association studies (GWAS) have provided new insights into the complexity of the c-MYC locus. Interestingly, numerous cancer risk-associated SNPs map within a 2Mb gene desert surrounding c-MYC. One explanation for the presence of risk-associated SNPs in distal-interg…
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Background: The ovarian response to follicle stimulating hormone (FSH) stimulation in assisted conception cycles is variable. Although it would be beneficial to predict accurately the response of patients to FSH, to date no robust predictors of ovarian performance have been iden…
The aim of this thesis is to explore the role of common genetic variation, identified through genome-wide association (GWA) studies, in human traits and diseases, using height as a model polygenic trait, type 2 diabetes as a model common polygenic disease, and maturity onset dia…
The history of cotton breeding in the southeastern United States is multifaceted and complex. Public and private breeding programs have driven cotton’s genetic development over the past two centuries. The Pee Dee breeding program in Florence, South Carolina, has had a substantia…