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Num contexto histórico, a frequência de gestações trigemelares atingiu o seu auge nos finais do século XX e diminuiu significativamente a partir de então, registando-se atualmente uma frequência de 0,2 por 1000 grávidas. Atualmente, os grandes fatores etiológicos que estão na or…

In this series of studies, three issues were addressed. First, the prevalence of undiagnosed diabetes (high fasting blood glucose with no prior diagnosis of diabetes) and how different they are from the diagnosed diabetes in risk factors. Second, the prevalence and risk factors …

In type 1 diabetes (T1D), islet-reactive T cells infiltrate the islets but they are well tolerated for a long period of time in a stage known as benign insulitis. Progression from benign insulitis to destructive insulitis and diabetes is thought to be regulated. In this study we…