God Damn is a poetic collection that delves into the complex relationship between a daughter and her father, who has recently suffered from a stroke. As her father grapples with Aphasia, a neurological disorder which has rendered him with a uniquely limited vocabulary, the autho…
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Stroke is a critical health issue that largely affects individuals’ overall life. Sleep-related factors are emerging risk factors of stroke, and their relationships with stroke have been less investigated compared to other risk factors. The purpose of this study was to examine w…
Background: Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. CVD mainly comprise of coronary heart disease and stroke and were ranked first and fourth respectively amongst leading causes of death in the United States. Influenza (flu) caus…
Among cerebral disorders, brain aneurysm (BA) is distinguished by tragic and serious neurological complications. The ballooning of brain arteries is a common pathology at all ages and associated with high mortality and morbidity rates. Recent BA related studies in medical and en…
To study if there is any association of caffeine with mortality secondary to cardiovascular disease in survivors of myocardial infarction (MI) and stroke, we used the Third National Health and Nutrition Examination Survey and the Linked Mortality File. Out of 1083 survivors of s…
Cerebral ischaemia, or stroke, is a leading cause of death and disability worldwide. Ischaemic stroke, as a result of arterial occlusion, and subarachnoid haemorrhage (SAH), as a consequence of arterial rupture in the subarachnoid space, are major subtypes of stroke. Treatment o…
Stroke is one of the leading causes of disability with over three-quarters of patients experiencing an upper limb impairment varying in severity. Early, intense, and frequent physical rehabilitation is important for quicker recovery of the upper limbs and the prevention of furth…
Stroke is a major global health burden with limited therapeutic options. Two major subtypes of stroke exist, ischaemic stroke (IS) and intracerebral haemorrhage (ICH). IS occurs following cerebrovascular occlusion, whereas ICH occurs when a vessel bursts and blood enters parench…
Obesity is an independent risk factor for ischaemic stroke and may worsen stroke outcome. Therefore, the objective of this thesis was to identify potential interactions between obesity and stroke, with particular focus on inflammatory mechanisms. Ischaemic stroke was surgically …
This thesis was based on a collection of my published works. Chapter 1 introduced the idea that infections, both acute and chronic, were risk factors for stroke. Various infections and micro-organisms associated with stroke were discussed. Specifically, the relationship between …
Much previous work on air pollution epidemiology has studied end-stage outcomes such as mortality or severe ill health warranting emergency admission, often based on clinical criteria prone to misclassification, and usually without accompanying study of the mediating mechanisms.…
Background. It has become conventional wisdom that regular routine check-ups help early detection and control of many chronic diseases that have the potential to have adverse effects in late age and also cause premature death. Primary Care (PC) is intended to address early detec…
Background and objectives of the study. Hip fractures are prevalent among older adults and recognized to be a major public health problem in many Western nations. Hip fractures, particularly in elderly, result in loss of independence in ambulation, limits in activities of daily …
Medical knowledge and functional assessment are analyzed with scaled measurement instruments and qualitative data from interview narratives. Focusing on functional ability after an acute stroke event, this dissertation presents an account of functional independence in self-care …
Moyamoya (MMA) is a progressive cerebral steno-occlusive angiopathy which can lead to strokes. Its natural history derives from adult East Asian cohorts with idiopathic disease. Clinical differences in pediatric, non-Asian and syndromic patients are reported but understudied. Th…
In this dissertation, I conduct three studies focusing on differences in social groups and their health outcomes or opinions related to medical practices. In Chapter 1, I outline each study and its findings.
In order to develop more effective rehabilitative therapies for stroke patients, we must understand what biological barriers limit functional recovery. Here we study functional recovery after stroke in the visual domain where recovery can be easily quantified with visual field t…
This project focused on two concepts: a need for a stroke prevention program and what should be included. The problem with early identification of stroke is not formally addressed at the project site, physician’s office. A physician’s office can play a beginning key role in mini…