An important, contemporary focus of environmental sociology is on the necessary conditions to promote a sustainable transition. This debate typically centers institutions within a capitalist world-economy, specifically business, government, and civil society, and their capacity …
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Successful reproduction depends upon a highly orchestrated cascade of events during optimal environmental conditions in order to appropriately time ovulation. In spontaneously ovulating rodents, neurons in the hypothalamus secreting gonadotropin-releasing hormone (GnRH) are trig…
A field survey and a metabolism experiment were conducted to study livestock watering practices in the Moroccan Pre-Sahara and their changes with drought extent, season, ecological zone, pastoral system and herd size. The metabolism experiment was designed to determine effects o…
One of the major limitations of aquaculture has been the inefficient digestion of phytate-bound phosphorus in plant-based diets. The enzyme phytase has been found to degrade phytate into a form that can be utilized by non-ruminant animals. The goal of this research was to produc…
Systems biology attempts to understand biological systems through the generation of predictive models that allow the behaviour of the system to be simulated in silico. Metabolic systems biology has in recent years focused upon the reconstruction and constraint-based analysis of …
Obesity is an independent risk factor for ischaemic stroke and may worsen stroke outcome. Therefore, the objective of this thesis was to identify potential interactions between obesity and stroke, with particular focus on inflammatory mechanisms. Ischaemic stroke was surgically …
The experiments herein examine the behavioral and physiological responses involved in the metabolic control of reproduction using Syrian hamsters ( Mesocricetus auratus) and sheep (Ovis aries) as animal models. The hamster reproductive cycle is sensitive to energy availability, …
The objective of this study was to determine if selection for increased breast muscle mass has affected the supracoracoideus muscle's ability to regulate pH during physical activity in turkeys. The lightweight male line (LM) had the greatest breast muscle mass as a percent of bo…
Smoking is a major preventable cause of death throughout the world and the need for cessation is unanimously supported by clinicians and scientists. Nicotine in cigarettes is believed to cause tobacco dependence and addiction and low doses of nicotine are found in nicotine repla…
Objective of this study was to evaluate effect of UV-C radiation (0, 1.16 and 3.21 kJ/cm2), pomegranate (Punica granatum) seed essential oil (PGEO) and lemon (Citrus lemonum) plant essential oil (CLEO) on decontamination of Candida albicans, Listeria monocytogenes, Staphylococcu…
Targeting of the narrow therapeutic index (NTI) drug warfarin is very challenging for patients and physicians alike. That's because subtherapeutic warfarin level can cause recurrence of the thromboembolic events while supratherapeutic level may significantly raise the bleeding r…
Cysteine proteases cathepsins are lysosomal enzymes that regulate numerous lysosomal functions but were also appreciated for their extra-lysosomal activities and their contribution to various pathologic conditions. Given the diversity in cathepsin function, we set out to explore…
Amaç: Bu çalışmada, özellikle Balkanlar ve Türkiye'de tamamlayıcı tıp uygulamalarında yaygın olarak kullanılan Cotinus coggygria (tetra otu) bitkisinde bulunan ağır metal düzeylerinin tayin edilmesi amaçlanmıştır. Gereç ve Yöntem: Güney merkez Bulgaristan’da yer alan Haskova ve …
Amaç: Bu çalışmada sıçanlarda streptozotosin ile oluşturulan diyabet modelinde kardiyovasküler komplikasyonları etkileyebilecek miRNA'ların kalp dokusundaki ekspresyon düzeylerine bakılması amaçlanmıştır. Gereç ve Yöntem: Çalışmamızda, 300-400 gr arasındaki ağırlıkta olan Spragu…
Amaç: Son yıllarda yapılan çalışmalar Myrtus Communis L. (MC) ekstraktının antioksidan ve antidiyabetik özelliklerini ortaya koymaktadır. Bu çalışmadaki hedefimiz bu ekstraktın yüksek yağlı diyet (YYD) ile beslenen sıçanların pankreası üzerinde etkilerini ortaya koyabilmektir. G…
Protein Tyrosine Phosphatase 1B is a critical regulatory phosphatase for a wide host of cellular processes. Here, we characterize the association between Protein Tyrosine Phosphatase 1B and Fatty Acid Synthase (FAS) in Brown Adipocytes and in mice. Using the combination of subst…
Introduction: The stress response is the complex physiological reaction that emerge in the face of a significant threat to bodily integrity or wellbeing. While the stress response is considered adaptive, over-activation of the stress response could be maladaptive and may lead to…
Understanding the origin and elaboration of complex traits is of fundamental interest to scientists and non-scientists alike. Darwin was the first to propose a mechanistic explanation for the evolution of complex traits by suggesting that complexity can evolve by a gradual stepw…
Metabolic rate is intricately linked to the ecology of organisms and can provide a framework to study the behaviour, life history, population dynamics, and trophic impact of a species. Acquiring measures of metabolic rate, however, has proven difficult for large water-breathing …