Over the past decades, an immense pandemic of obesity has been developing across the world, in part due to an overabundance of food that is available 24/7. While in ancient history a major need existed to store spare energy for times when food was scarce, the energy-conserving a…
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Lipids are important for the structural and physiological functions of neuronal cell membranes. Alterations in their lipid composition may result in membrane dysfunction and subsequent neuronal deficits that characterise various disorders. This study focused on profiling lipids …
The thesis investigated the effect of exercise on endothelial function (measured as flow-mediated dilation (FMD)) and triacylglycerol concentrations following the ingestion of a high-fat breakfast and lunch in adolescent boys. The validity of measuring lipid and lipoprotein conc…
Considering the response of organisms to their environment is difficult; it is made more so if population numbers cannot be closely monitored. In such cases different methods of population assessment are required. This thesis uses lipids as a measure of Atlantic salmon (Salmo sa…
Cysteine proteases cathepsins are lysosomal enzymes that regulate numerous lysosomal functions but were also appreciated for their extra-lysosomal activities and their contribution to various pathologic conditions. Given the diversity in cathepsin function, we set out to explore…
The purpose of this study is to manufacture structured lipids by enzymatic and chemical interesterification of tallow with corn, canola and safflower oils individually and to investigate the effects of several process parameters on various chemical and physical properties of str…
Gangliosides are sialic acid containing biomolecules and perform important functions by locating on cell membranes. Their catabolism regulated by sialidases while their synthesis was performed by glycosyltransferases. Neu3 reacts with gangliosides on plasma-membrane and acts in …