Interrogation of the chemical composition of rocky planets provides a deeper understanding of the history and evolution of the solar system. While laboratory studies of returned samples and remote sensing surveys of planetary surfaces can give insight into planetary history, one…
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In-situ mass spectroscopy is used to sense plasma deposition of silicon and silicon nitride to analyze gas phase reactant depletion, and the efficiency of silane conversion into the thin film. In-situ mass spectroscopy and mass balance modeling have been used to quantify deposit…
Pre-treatment with polyunsaturated fatty acids or bioactive lipid mediators has been shown to reduce neuronal injury in rodent models of focal ischaemia, but the molecular mechanisms underlying this neuroprotection are unclear. In this study, we aimed to investigate whether syst…
The primary purpose of this study was to investigate the combination of experimental and computational methods in the search for reproducible colloidal surface-enhanced Raman scattering of pharmaceutical compounds. In the search for optimal experimental conditions for colloidal …
Targeting of the narrow therapeutic index (NTI) drug warfarin is very challenging for patients and physicians alike. That's because subtherapeutic warfarin level can cause recurrence of the thromboembolic events while supratherapeutic level may significantly raise the bleeding r…
Cell-free circulating DNA (cfDNA) released from dying cells is emerging as an important tool for the diagnosis of disease. However, the utility of cfDNA is limited in conditions in which involved tissues have a normal genome or unknown mutations. I have developed an approach to …
Recently emerged perovskite materials show superior features like high efficiency, defect tolerance, facile synthesis, bandgap tunability and wide color gamut over their rivals in photonics applications. On the other hand, metals have interesting characteristics as they go small…
The effects of direct plasma chemistries on carbon removal from silicon nitride (SiNx ) and oxynitride (SiOx Ny ) surfaces and Cu have been studied by x-photoelectron spectroscopy (XPS) and ex-situ contact angle measurements. The data indicate that O2 ,NH3 and He capacitively co…
Avian pathogenic strains of Escherichia coli serotypes O2, O35 and O78 cause air sac infections in turkeys, but the reason for the colonization of these serotypes is unknown. Air sac surface fluid (ASSF) from 8–12 weeks old turkeys was examined to identify proteins that bind sur…
The ZaP-HD Flow Z-Pinch device was designed to investigate the use of a tri-axial electrode configuration to scale a sheared-flow stabilized Z pinch to high energy density conditions. Decoupling the power used to form the plasma from the power used to compress the pinch has resu…
Blood is a critically important human tissue, and for over a century, blood transfusions have saved the lives of countless patients. However, blood is often in short supply, and the cost of screening donated blood for immune compatibility and an ever-increasing number of blood-b…
Climate change is one of the major challenges of our current era. The amount of greenhouse gas emissions produced by anthropogenic sources has steadily increased since the industrial revolution, in particular CO 2 , which reached a maximum historical concentration of 409.8 ppm i…
It was reported that the plasma pharmaceuticals industry exceeded 20 billion in market value in 2016, with U.S. donors accounting for roughly 70% of the world’s collected plasma. Since being subjected to market forces blood collection and exchange have raised ethical questions a…
This dissertation discusses the modeling of breakdown of gases under nano-second laser discharges, the plasma kernel dynamics, the plasma core decay, and the subsequent post-dischargee hydrodynamics, together with some of its engineering applications (e.g., flow control and igni…
IntroducaoA transfusão dos eritrócitos é a base para o tratamento de doentes com hematopoiese comprometida e para doentes com perdas significativas de sangue. Após a transfusão de eritrócitos, existe contacto com antigénios, nomeadamente, estruturas de polissacarídeos e proteína…