There is a high prevalence of hypertension in Nigeria. Limited knowledge of hypertension, how to prevent it, its outcomes, rapid urbanization, and the adoption of Western eating habits are implicated. Hypertension is an important issue because chronic disease places economic, so…
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According to the World Health Organization (WHO), Pakistan is facing a rapid rise in non-communicable diseases associated with lifestyle changes in urban cities. Nutrition and diet are key components of lifestyle modification factors that can help prevent and reduce the disease …
Hypertension is a potent, yet preventable disease worldwide. Research supports the need for strict adherence to antihypertensive regimens in order to prevent complications associated with the disease. Adherence to hypertensive regimens among rural populations in Nigeria is under…
The dissertation is divided into three manuscripts. The first manuscript reviews the literature on HTN status in Arab countries and identifies promising areas for future research and interventions. This review of literature revealed that HTN is prevalent among Arabs and supporte…
The determinants of hypertension (HT) in West Africa have not been well defined. In this study we sampled 598 men and women, 45 years of age and older, from a recently completed population-based survey in southwest Nigeria; 190 men and women from a rural area, 205 men and women …
Hypertension is associated with end organ damage (EOD). Since EOD is a risk factor for cardio- and cerebrovascular complications, it is a major requirement for these to be detected, prevented and treated. A total of 147 consecutive patients with newly-diagnosed essential hyperte…
The common human GNB3 825C > T variant, which is present in 50% of the world’s chromosomes, has previously been shown to predispose individuals to hypertension, cardiac and neural disorders. This variant causes the production of a stable and gain of function protein Gβ<sub>3S</s…
Human placental villi are covered by a layer of trophoblast epithelia in direct contact with maternal blood, which exist in a constant steady-state of turnover and renewal ensuring both maternal and fetal health. The process of trophoblast turnover involves proliferation, differ…
An optimal BMI cutoff is needed in public health and clinical settings as the guidance an optimal body weight. Although body mass index (BMI) cutoffs of 25 and 30 kg/m2 for overweight and obesity, respectively, have been widely used among Westerners and recommended by the World …
Introduction. High-stress situations, such as military deployments, may be a risk factor for hypertension. The relationship between the stress triggered by combat deployment and hypertension is unknown. Acute stress from combat conditions can cause a temporary rise in blood pres…
The objectives of this dissertation are to: (1) assess the validity of a food frequency questionnaire (FFQ) designed for the Health Effects of Arsenic Longitudinal Study (HEALS); (2) examine the associations between intakes of major dietary factors, dietary patterns and blood pr…
Background. It has become conventional wisdom that regular routine check-ups help early detection and control of many chronic diseases that have the potential to have adverse effects in late age and also cause premature death. Primary Care (PC) is intended to address early detec…
Cardiovascular disease is the leading cause of death in Colombia. However, in Colombia both the prevalence and social distribution of hypertension, the main risk factor for cardiovascular disease, have been understudied. Likewise, although macroeconomic factors have been highlig…
Racial and ethnic minorities in the United States have higher rates of hypertension than European Americans. In this ethnographic study, 30 Nigerian immigrant health care workers with hypertension described their self-efficacy management of the disease to ascertain the relations…
Background. Angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) are essential to the treatment of heart failure with reduced ejection fraction (HFrEF). However, little data are available to determine whether their efficacy in reducing hospital…
Amaç: Hipertansiyon kanda ve dokularda reaktif oksijen türlerinin üretiminde artıĢa ve antioksidan kapasitenin düĢüĢüne sebep olmaktadır. Antioksidanların anjiyotensin dönüĢtürücü enzim sistemini inhibe ettiği bilinmektedir. ÇalıĢmamızda, antioksidan etkisi bilinen mersin bitkis…
Pulmonary Arterial Hypertension (PAH) is a sever disorder characterized by high pulmonary artery pressure and pulmonary vascular resistance along with specific histological changes. Idiopathic PAH is a human disease of unknown origin that showed common characteristics to PHS/asc…
Der primäre Hyperaldosteronismus ist die häufigste Ursache einer sekundären Hypertonie. Ein Aldosteronüberschuss kann in vitro und in vivo DNA-Schäden verursachen. In einzelnen Fallberichten wurde über eine Koinzidenz des primären Hyperaldosteronismus mit Nierenzellkarzinomen wi…