Lysophosphatidic acid (LPA) is known to exert a diverse range of effects in humans, specifically in the heart where it may cause apoptosis of cardiomyocytes at pathological concentrations. However, at physiological concentrations LPA may regulate cell migration, proliferation an…
Obesity affects about 520 million people world-wide and more recently studies have shown that fat cells produce proteins called adipokines which have various influences on the human metabolism and has helped to change the perspectives of researchers on the concept of the adipose…
Background: It is unknown whether the common antidepressant, venlafaxine, is associated with increased cardiovascular risk. Objective: To examine the cardiac safety of venlafaxine in older individuals. Methods: A population-based retrospective cohort study (Ontario, Canada) comp…
Posttraumatic stress disorder (PTSD) is associated with increased risk for cardiovascular disease and relationship difficulties. Greater exposure to couple conflict, and greater emotional and cardiovascular reactivity to such conflict, may help explain the link between PTSD and …
Heart disease is responsible for one in four deaths in the United States. Atherosclerotic Cardiovascular Disease (ASCVD) screening tools can help with risk stratification and treatment of low, intermediate, and high-risk patients before an event such a myocardial infarction or s…
Childhood stress has been correlated with deleterious health outcomes and illnesses such as cardiovascular disease (Felitti et al., 1998; Su et al., 2014). The biopsychosocial model of health conceptualizes childhood development and identifies possible mechanisms of this relatio…
Cardiovascular diseases represent a significant portion of deaths among women in the United States. Research has suggested that abuse and violence may be risk factors for cardiovascular diseases. Nearly 1 in 3 women in the United States have experienced some form of sexual viole…